St George Illawarra overcome an early deficit to beat the Titans 32-18 at Netstrata Jubilee Stadium in Kogarah.
The Titans shot out of the blocks with tries to Alofiana Khan-Pereira and Sam Verrills setting up a 12-2 lead but their advantage was evaporated by half-time with the Dragons running in three tries in eight minutes before the break.
Dragons halfback Ben Hunt and fullback Tyrell Sloan were among the stars in their first showing of the season with the side putting their Charity Shield performance behind them and enjoying the benefit of an additional week off.
Dragons recruit Jacob Liddle finished off a Sloan break up the middle in the 31st minute before Hunt weaved his way to the line via a Zac Lomax offload shortly after.
St George Illawarra hit the lead when Mikaele Ravalawa crossed eight seconds before half-time as poor discipline started to prove costly for the visitors.
It continued after the break with Tanah Boyd unable to find touch from a penalty which enabled Hunt to send Sloan over from close range in the following set.
More ill-discipline allowed Lomax to take a second penalty goal of the game as the Titans' kicking game into the breeze was questionable.
Justin Holbrook opted for Jayden Campbell's injection into the game with 15 minutes to go but it meant little when Blake Lawrie moments later to set up a dominant lead.
A try to Tino Fa'asuamaleaui with 10 minutes left added to the scoreboard as the Dragons notched up a comfortable win.
What's next
Both sides have a six-day turnaround and will feature in Queensland next Saturday night. The Titans take on Melbourne at Cbus Super Stadium for their first home game of the year while the Dragons will meet the Broncos at Suncorp Stadium. Jack de Belin (calf) could be back for the Dragons while Brian Kelly will have served his suspension for the Titans.